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For HOPPS rate setting purposes, CMS should treat 77402, 77407, and 77412 as new codes. Several commenters suggested alternative APC assignments, recommending that CPT code 77407 be reassigned from APC 5622 to APC 5623 (Level 3 Radiation Therapy), which has a CY 2026 proposed payment rate of around $600

Vitamin B12 deficiency may be treated with oral supplements or intramuscular injections depending on severity

As diclofenac metabolites are eliminated primarily by the kidney, patients with renal insufficiency close monitoring of the patient's renal function is advisable

5-Amino-1MQ, being a stable small molecule, is generally easier to store and handle without degrading